Primary Pulmonary MALT Lymphoma about Four Cases and Literature ReviewEl Haouari A2*, Tahiri L2, Moumna K2, Remmilink M1 and Salmon I1
- *Corresponding Author:
- Aziza El Haouari
Department of Pathology
Hassan Ii Teaching Hospital
Tel: +212 72400059
E-mail: [email protected] hotmail.fr
Received date: Febuary 25, 2015; Accepted date:December 29, 2015; Published date: December 31, 2015
Citation: El Haouari A, Tahiri L, Moumna K, Remmilink M, Salmon I (2015) Primary Pulmonary MALT Lymphoma about Four Cases and Literature Review. J Pulm Respir Med 5:307. doi:10.4172/2161-105X.1000307
Copyright: © 2015 El Haouari A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Bronchial-associated lymphoid tissue (BALT) lymphoma is a distinct subgroup of low-grade B-cell extranodal non- Hodgkin’s lymphoma, classified as marginal-zone lymphoma. This study was performed in order to assess the natural history of this rare entity. We evaluated retrospectively the clinical, radiological and histological features and to discuss the optimal management and prognostic factors through a literature review, of 4 patients with biopsy-proven BALT lymphoma collected at department of pathology of Erasme from 2010 to 2014. The group of four patients included tree women and one man, with a median age of 69 years (Range: 45-84 years). One of 4 patients presented fever chest pain within bronchopneumonia, other patients were asymptomatic with an incidental finding after preoperative radiological assessment.
Computed tomography (CT), which is more sensitive than standard radiography, has demonstrated that the lesions are unilateral (n=3) and multiple (1 patient), without lymph node enlargement. All of our patients has a thoracoscopy diagnosis and therapeutic. Macroscopy: whitish lesions poorly defined. Microscopy: MALT lymphoma low grade (CD20 +, bcl2+). All of our patients have just a local treatment without chemotherapy and three were alive after a follow extended.