alexa Primary Synovial Sarcoma of the Mediastinum: A Case Report and Review of the Literature | OMICS International | Abstract
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Primary Synovial Sarcoma of the Mediastinum: A Case Report and Review of the Literature

Ouji M1, Souissi S2, Mbarek K3, Koubaa M4 and Mezghani Boussetta S1*
1Department of Radiology, Regional Hospital of Ben Arous, Tunisia
2Department of Pulmonology, Regional Hospital of Ben Arous, Tunisia
3Department of Emergency, Regional Hospital of Ben Arous, Tunisia
4Department of Pathology, Habib Thameur Hospital, Tunis, Tunisia
Corresponding Author : Mezghani Boussetta S
The faculty of Medicine of Tunis
Department of Radiology, University EL manar 2
15 Rue Djebel Alkhdhar, La Rabita, 1007, Tunis, Tunisia
Tel: +216 71 872 253
E-mail: [email protected]
Received May 27, 2015; Accepted June 23, 2015; Published June 24, 2015
Citation: Ouji M, Souissi S, Mbarek K, Koubaa M, Mezghani Boussetta S (2015) Primary Synovial Sarcoma of the Mediastinum: A Case Report and Review of the Literature. J Clin Case Rep 5:548. doi:10.4172/2165-7920.1000548
Copyright: © 2015 Ouji M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Synovial sarcomas most commonly occur in the soft tissues of the extremities of young adults. A
primary occurrence in the mediastinum is very rare with only a few reported cases in the world literature.
Study aims: to insist on the rarity of this pathology, its imaging features and the importance for recognizing
unusual presentation of this aggressive neoplasm to aid appropriate clinical management.
Cases: Here in, we report a rare case of primary monophasic spindle cell synovial sarcoma of the mediastinum
in a 31-year-old man who had an incidental finding of such a tumor. The imaging studies on admission showed 12 cm
anterior- middle mediastinal mass with multiple metastases in the lung, pleura, mediastinal lymph nodes and spine.
An ultrasound-guided percutaneous needle biopsy of a cervical extension of the mass permitted histopathology and
immuno histochemical analysis which supported the diagnosis of monophasic spindle cell synovial sarcoma. The
patient was treated by chemo-therapy without response.
Conclusion: A wide range of neoplasms both primary and metastatic occurs in the mediastinum which poses
considerable diagnostic difficulties. A synovial sarcoma should be considered in the differential diagnosis. Imaging
can guide percutaneous needle biopsy of the tumor and evaluate its stage. Immunohistochemistry can be very
helpful for an accurate diagnosis

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