Primary Vaginal Melanoma Cytohistological Correlates and Literature Reviews
Anani Aila Mat Zin* and Nur Syuhada Mohd Nafis
Department of Pathology, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
- *Corresponding Author:
- Anani Aila Mat Zin
Department of Pathology, Health Campus
Universiti Sains Malaysia, Kubang Kerian
E-mail: [email protected]
Received date: July 29, 2015; Accepted date: August 05, 2015; Published date: August 12, 2015
Citation: Zin AAM, Nafis NSM (2015) Primary Vaginal Melanoma – Cytohistological Correlates and Literature Reviews. Gynecol Obstet (Sunnyvale) 5:312. doi:10.4172/2161-0932.1000312
Copyright: © 2015 Zin AAM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Malignant melanoma is a well known high grade tumor but with slowly progressing malignancy. Primary malignant melanoma is a rare, highly malignant and has a poor prognosis disease. A 54-years-old, pre- menopause female presented with a mass coming out of vagina with foul smelling vaginal discharge and prolonged vaginal bleeding for 3 months. On per speculum examination, there was a friable greyish fungating mass measures 5×3 cm in size with contact bleeds which predominantly involved the vagina. Pap smear was done and reported as carcinoma (NOS). Later, biopsies were done at various sites around cervix, vaginal mass, left vaginal tumour margin and endometrial. Cervical and endometrial biopsies show no evidence of malignancy. However, the biopsy from vaginal mass reported as malignant melanoma of vagina. The left vaginal wall margin also shows tumour involvement. The patient was received an external pelvic radiotherapy. CT scan staging shows the malignant tumour has metastasized to the lung and liver. Currently patient is under chemotherapy follow up.