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Processing and Characterization of Silicon Nitride Bioceramics | OMICS International | Abstract

Bioceramics Development and Applications
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Research Article

Processing and Characterization of Silicon Nitride Bioceramics

Bryan J. McEntire1*, Ramaswamy Lakshminarayanan2, Prabhakar Thirugnanasambandam3, Jacob Seitz-Sampson1, Ryan Bock1 and David O’Brien1

1Amedica Corporation, 1885 West 2100 South, Salt Lake City, UT 84119

2Corning, Inc., SP-FR-04, Corning, NY 14831

3Prismatik Dentalcraft, Inc., 2181 Dupont Dr., Irvine, CA 92612

Corresponding Author:
Bryan J McEntire
Chief Technology Officer, Amedica Corporation
1885 West 2100 South, Salt Lake City, UT 84119, USA
Tel: 8018393504
E-mail: [email protected]

Received date: April 25, 2016; Accepted date: May 23, 2016; Published date: May 30, 2016

Citation: McEntire, BJ et al. (2016) Processing and Characterization of Silicon Nitride Bioceramics. Bioceram Dev Appl 6:093. doi:10.4172/2090-5025.1000093

Copyright: © 2016 McEntire BJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


As a relatively new biomaterial, silicon nitride (Si3N4) is currently used as an arthrodesis device in the cervical and thoracolumbar spine, and it is under consideration as a bearing material in total joint arthroplasty. In this paper, the development and validation of the manufacturing processes used in the production of Si3N4 biomedical implants are presented and discussed. Manufacturing was conducted in a facility specifically dedicated for this purpose using processes designed to yield net shape intervertebral spinal spacers by conventional dry-pressing, CNC machining of components in the green state, sintering, and hot isostatic pressing. These manufacturing methods were industrialized using Taguchi fractional factorial experimental designs, followed by implementation of statistical process controls. The roles of various processing parameters including raw materials, pressing, and firing conditions (i.e., time, temperature, and pressure) are elucidated. For these devices, it was demonstrated that acceptable physical, mechanical, and dimensional properties were consistently obtained from carefully designed and statistically controlled processes.