alexa Prognostic Factors of Pregnancy after Homologous Intrau
ISSN: 2167-0250

Andrology-Open Access
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Research Article

Prognostic Factors of Pregnancy after Homologous Intrauterine Insemination

Zorn B1*, Verdenik I2, Kolbezen M1 and Vrtačnik Bokal E1
1Andrology Unit, Division of Obstetrics and Gynaecology, University Medical Centre Ljubljana, Ljubljana, Slovenia
2Research Unit, Division of Obstetrics and Gynaecology, University Medical Centre Ljubljana, Ljubljana, Slovenia
*Corresponding Author : B Zorn
Andrology Unit, Division of Obstetrics and Gynaecology
University Medical Centre Ljubljana
Šlajmerjeva 3, 1000 Ljubljana, Slovenia
Tel: 0038615226072
E-mail: [email protected]
Rec date: February 16, 2016; Acc date: March 14, 2016; Pub date: March 21, 2016
Citation: Zorn B, Verdenik I, Kolbezen M, Vrtacnik BE (2016) Prognostic Factors of Pregnancy after Homologous Intrauterine Insemination. Andrology (Los Angel) 5:154. doi:10.4172/2167-0250.1000154
Copyright: © 2016 Zorn B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

The objective was to identify the factors influencing the outcome of homologous intrauterine insemination (IUI-H). Nine hundred and sixty-eight couples underwent 2246 IUI-H cycles. The clinical pregnancy rate (PR) per IUI-H cycle and per couple, and the miscarriage and multiple pregnancy rates were 11.8%, 27.4%, 23.3%, and 12.0%, respectively. IUI-H for combined infertility (n = 118) was 3 times less efficient than IUI performed for unexplained infertility (n = 289), OR = 0.293 (95% CI, 0.098-0.872). PRs did not differ in CC, letrozole and gonadotropin cycles, but compared with CC, Gonal-F was twice as efficient, OR = 1.994 (95% CI, 1.137-3.495). The cycles with at least 3 follicles ≥17 mm were twice as successful as the cycles with 1 follicle only, OR = 1.836 (95% CI, 1.061-3.177). The success of IUI-H increases with higher inseminated motile sperm count (IMC), from 3.6×106 up to 12×106, where it reaches a plateau.

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