alexa Prognostic Value of Heart Rate Reserve in Exercise Treadmill Test after Coronary Revascularization | OMICS International | Abstract
ISSN: 2165-8048

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Research Article

Prognostic Value of Heart Rate Reserve in Exercise Treadmill Test after Coronary Revascularization

Seung Pyo Hong, Young Soo Lee*, Jin Bae Lee, Jae Kean Ryu, Ji Yong Choi and Kee Sik Kim
Department of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea
*Corresponding Author : Young Soo Lee
Department of Cardiology
Daegu Catholic University Medical Center
3056-6, Daemyung-4-dong, Nam-gu, Daegu, Korea
Tel: 82-53-650-3041
Fax : 82-53-621-3166
E-mail: [email protected]
Received August 14, 2014; Accepted October 15, 2014; Published October 22, 2014
Citation: Hong SP, Lee YS, Lee JB, Ryu JK, Choi JY, et al. (2014) Prognostic Value of Heart Rate Reserve in Exercise Treadmill Test after Coronary Revascularization. Intern Med 4:175. doi:10.4172/2165-8048.1000175
Copyright: © 2014 Hong SP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: The aim of this study was to assess heart rate (HR) responses to exercise in the prediction of the major adverse cardiovascular events (MACE) in patients with revascularization. Methods: We retrospectively analyzed 253 patients with successful revascularization and exercise treadmill test (ETT) 4 months later in asymptomatic status. MACE was defined as cardiac death, nonfatal myocardial infarction and revascularization. HR reserve as index of chronotropic response was calculated as (peak HR-baseline HR) ×100/(220-age-baseline HR). Impaired HR reserve was defined as achievement of <80% in patients without betablockers (BB) and <62% in patients with BB. HR recovery at 1minute (HRR 1min) was calculated as peak HR–HR at recovery 1minute. Impaired HRR 1min was defined as a decrease of ≤12bpm. Results: HRR 1min and HR reserve were significantly lower in MACE group. In multivariate analysis, HRR 1min and HR reserve were independent predictors for the MACE. The odds ratios (OR) for the MACE in impaired HRR 1min was 4.7 with adjustment. In addition, the OR for the MACE in impaired HR reserve was 4.4 with adjustment. Moreover, the OR for the MACE in patients with both impaired HRR 1min and impaired HR reserve was 7.5 with adjustment. Conclusions: Impaired HRR 1min and HR reserve to exercise could be associated with the MACE in the asymptomatic patients with successful revascularization.

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