alexa Progressive Multifocal Leukoencephalopathy in Africa┬ľA Review
ISSN: 2376-0389

Journal of Multiple Sclerosis
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Progressive Multifocal Leukoencephalopathy in Africa┬ľA Review

Clara-M Schutte*

Department of Neurology, University of Pretoria, Steve Biko Academic Hospital, South Africa

Corresponding Author:
Clara- M Schutte
Department of Neurology
University of Pretoria
Steve Biko Academic Hospital, South Africa
Tel: +27 12 354 1082
Fax: +27 12 354 2045
E-mail: [email protected]

Received date: August 04, 2014; Accepted date: September 16, 2014; Published date: September 22, 2014

Citation: Schutte C-M (2014) Progressive Multifocal Leukoencephalopathy in Africa–A Review. J Mult Scler 1:114. doi:10.4172/2376-0389.1000114

Copyright: © 2014 Schutte C-M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Progressive multifocal leukoencephalopathy caused by the JC virus, results in a lytic infection of mainly oligodendrocytes of the central nervous system in immunosuppressed patients. With the advent of the HIV pandemic, the incidence of PML has risen sharply, but very few cases from Africa have been reported, even though this continent carries a very high burden of HIV infection. Explanations for the paucity of reports of PML from Africa include non-recognition of the condition, diagnostic challenges, death due to other infections, as well as suggestions of decreased neurovirulence of African JC virus types, and interactions between these types and different HIV clades. In this report we focus on reports of cases with PML from Africa, suggesting that with the availability of more sensitive assays and greater awareness, the diagnosis of PML may be more readily made in the future.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version