Prophylaxis of Deep Venous Thrombosis in Trauma Patients: A Review
Jonas P DeMuro* and Adel F Hanna
Department of Surgery, Division of Trauma, Critical Care and Emergency General Surgery, Winthrop University Hospital, USA
- Corresponding Author:
- Jonas P DeMuro
Department of Surgery, Division of Trauma
Critical Care and Emergency General Surgery
Winthrop University Hospital, USA
E-mail: [email protected]
Received Date: May 28, 2013; Accepted Date: July 29, 2013; Published Date: August 04, 2013
Citation: DeMuro JP, Hanna AF (2013) Prophylaxis of Deep Venous Thrombosis in Trauma Patients: A Review. J Blood Disord Transfus 4:151. doi: doi: 10.4172/2155-9864.1000151
Copyright: © 2013 DeMuro JP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Trauma patients are at high risk for venous thromboembolism. While a variety of risk factors predispose them to deep venous thrombosis and pulmonary embolism, the goal of aggressive chemical prophylaxis needs to be balanced against the risk of hemorrhage, making this a most challenging population to adequately prophylax. The use of titration of the prophylaxis to ant factor Xa levels is discussed. Special consideration needs to be taken in some particularly challenging trauma subpopulations, including those with renal failure, nonoperatively managed solid organ injury, traumatic brain injury with intracranial hemorrhage, spinal cord injury and the bariatric trauma patient, which are reviewed.