Propofol Requirement during Propofol and Butorphanol Anesthesia with and without Nitrous Oxide in Short Duration Intracranial Surgeries: A Bispectral Index Guided Study
Surya Kumar Dube*, Rajeev Kumar Dubey and Lal Dhar Mishra
Department of Anesthesiology and Intensive Care, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
- *Corresponding Author:
- Dr. Surya Kumar Dube
Department of Anaesthesiology and Intensive Care
Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
E-mail: [email protected]
Received date: June 12, 2012; Accepted date: September 06, 2012; Published date: September 20, 2012
Citation: Dube SK, Dubey RK, Mishra LD (2012) Propofol Requirement during Propofol and Butorphanol Anesthesia with and without Nitrous Oxide in Short Duration Intracranial Surgeries: A Bispectral Index Guided Study. J Anesth Clin Res 3:238. doi: 10.4172/2155-6148.1000238
Copyright: © 2012 Dube SK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Propofol is a preferred agent in neurosurgical anesthesia because of its favorable effects on cerebral hemodynamics and excellent recovery profile. Butorphanol is a synthetic opioid which is 5-8 times more potent than morphine and is known to provide stable hemodynamics during various surgical procedures. Owing to its unfavorable effects on cerebral metabolism and hemodynamics nitrous oxide has a debatable role in neurosurgical anesthesia. But studies on exact dose requirement during propofol induction and maintenance anesthesia along with butorphanol with and without the use of N2O during craniotomies are lacking. So we aimed at studying the requirement of propofol (used along with butorphanol) with and without the use of nitrous oxide in intracranial surgeries using bispectral index (BIS) monitoring.