Prospective Application of Lipidomics in Prostate CancerXinchun Zhou*
Department of Pathology, University of Mississippi Medical Center, USA
- *Corresponding Author:
- Xinchun Zhou
Department of Pathology
University of Mississippi Medical Center
2500 North State Street, Jackson
MS 39216, USA
E-mail: [email protected]
Received date: May 30, 2014; Accepted date: June 28, 2014; Published date: July 02, 2014
Citation: Zhou X (2014) Prospective Application of Lipidomics in Prostate Cancer. J Glycomics Lipidomics 4:114. doi: 10.4172/2153-0637.1000114
Copyright: © 2014 Zhou X. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Lipidomics, a rapidly developing research field, has been widely studied in many non-cancer areas, and in some
cancers. Taking prostate cancer as an example, this article has concisely reviewed applications of lipidomics in cancer
research. Lipidomics is able to identify a few out of thousands individual lipid species in bio-fluids as biomarkers in
diagnosis of prostate cancer with high sensitivity, specificity and accuracy. This technology has been also used in studying
the pathogenesis of prostate cancer by combining data of lipid profiling with lipid metabolites and pathways strategy.
Importantly, lipidomics can provide details of lipid compositions different between prostate cancer and benign prostate,
which will greatly help to make strategy in prevention and treatment of prostate cancer.