Protecting the Endothelial Cell Barrier
Atul D. Joshi * and John D. Catravas
Frank Reidy Center for Bioelectrics, Old Dominion University, Norfolk, USA
- *Corresponding Author:
- Atul D. Joshi
Frank Reidy Center for Bioelectrics
Old Dominion University, Norfolk, VA 23508, USA
Email: [email protected]
Received Date: January 30, 2015; Accepted Date: January 31, 2015; Published Date: Febuary 03, 2015
Citation: Joshi A (2015) Protecting the Endothelial Cell Barrier. J Cell Sci Ther 6:e120. doi: 10.4172/2157-7013.1000e120
Copyright: ©2015 Joshi A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Endothelial barrier dysfunction (EBD) is a major cause of various vascular diseases such as sepsis, acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) [1,2]. Current therapeutic strategies to mitigate these vascular pathologies involve administration of broad-spectrum antibiotics [3,4] and anti-cytokine antibodies [5,6] providing limited alleviation of symptoms and are clearly insufficient.