Protective Mechanical Ventilation and Tracheal Gas Insufflation in a Patient with Massive Pulmonary Embolism Caused by the Combined Deficiency of Proteins C and S and Antithrombin IIIJavier Mauricio Giraldo Sanchez*, Diana Lorena Giraldo Arboleda and Ricardo Andres Giraldo Arboleda
Intensive care (ICU), Critical Medicine and Intensive Care Colombian society, Science Director, Honda, Colombia
- *Corresponding Author:
- Javier Mauricio Giraldo Sanchez
Intensive care (ICU), Critical Medicine and Intensive Care Colombian society
Science Director, Honda, Colombia
Tel: 057 3158953193
E-mail: [email protected]
Received date: September 05, 2015 Accepted date: December 18, 2015 Published date: December 22, 2015
Citation: Giraldo Sanchez JM, Giraldo Arboleda DL, Giraldo Arboleda RA (2015) Patient with Massive Pulmonary Embolism Caused by the Combined Deficiency of Proteins C and S and Antithrombin III. J Pulm Respir Med 5:300. doi: 10.4172/2161-105X.1000300
Copyright: © 2015 Giraldo Sanchez JM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
During pulmonary embolism, the physiology of the ventilation and the perfusion is damaged. A sudden massive increase of the intrapulmonary shunt might result if the clinical setting is not adequately implemented to regulate the inflammatory process. For this reason, the protection of the ventilation and the tracheal gas insufflation are useful tools in modulating the injury, and the hypercoagulability caused by protein C and S and the deficiency of antithrombin lll. All caused by the damage of the endothelial barrier, therefore gives origin to interstitial leakage, tissue damage, inflammation, and apoptosis.