Review Article
Proteomics and Cholesterol in Autism
Alisa G Woods1,2*, Kelly L Wormwood1, Armand G Ngounou Wetie1, Jeanne P Ryan2 and Costel C Darie1
1Biochemistry & Proteomics Group, Department of Chemistry & Biomolecular Science, Clarkson University, 8 Clarkson Avenue, Potsdam, NY, 13699-5810, USA
2SUNY Plattsburgh Neuropsychology Clinic and Psychoeducation Services 101 Broad Street, Plattsburgh, NY, 12901, USA
- *Corresponding Author:
- Alisa G Woods
Biochemistry & Proteomics Group
Department of Chemistry & Biomolecular Science
Clarkson University, 8 Clarkson Avenue
Potsdam, NY, 13699-5810, USA
Tel: (315) 268-7763
Fax: (315) 268- 6610
E-mail: [email protected]
Received date August 02, 2013; Accepted date August 27, 2013; Published date September 04, 2013
Citation: Woods AG, Wormwood KL, Wetie AGN, Ryan JP, Darie CC (2013) Proteomics and Cholesterol in Autism. Autism 3:112. doi:10.4172/2165-7890.1000112
Copyright: © 2013 Woods AG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Autism Spectrum Disorder (ASD) diagnosis is increasing worldwide. ASDs are characterized by impaired social function, stereotyped behaviors/interests and communication deficits. ASD causes are poorly understood and treatments are largely limited to behavioral interventions once problems have developed and been detected. Here we discuss the potential use of mass spectrometry and proteomics in early diagnosis of ASD. The potential link between at least some subtypes of ASD, the cholesterol system and proteins that interact with cholesterol is also discussed.
