alexa Pseudoxanthoma Elasticum: Case Report
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

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Case Report

Pseudoxanthoma Elasticum: Case Report

Ayman Elgendy1*, Eslam Alshawadfy2, Eman Ali2, Magdy Afify3, Morad Abouelela3, Karem Khalil1 and Ahmed M Elsaidi4

1Department of Dermatology and Venereology, Benha University, Egypt

2Department of Dermatology and Venereology, National Research Centre, Cairo, Egypt

3Department of Dermatology, Ain Shams University, Cairo, Egypt

4Ain Shams University, Cairo, Egypt

*Corresponding Author:
Ayman Elgendy
Professor, Department of Dermatology and Venereology
Benha University, Egypt
Tel: 966507364687
E-mail: [email protected]

Received date: January 09, 2016 Accepted date: February 03, 2016 Published date: February 05, 2016

Citation:Elgendy A, Alshawadfy E, Ali E, Afify M, Abouelela M, et al. (2016) Pseudoxanthoma Elasticum: Case Report. J Clin Exp Dermatol Res 7:327. doi: 10.4172/2155-9554.1000327

Copyright: © 2015 Elgendy A, et al. This is an open-access article distributed under the terms of the Creative Co mmons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Pseudoxanthoma elasticum (PXE) is a hereditary disorder that mainly involves the skin, eyes, and cardiovascular system. We reported a case of pseudoxanthoma elasticum with involvement of neck, axillae, abdomen and thighs, together with angioid streaking of fundi. Skin biopsy specimen was taken and was stained with hematoxylin and eosin (H and E) that revealed fragmentation of the elastic fibers. These features were suggestive of histopathological diagnosis of PXE. We have reviewed other published reports to obtain a better understanding of the genetics, histopathology, vascular and ophthalmological manifestations of pseudoxanthoma elasticum.


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