Psychological Correlates in Subjects with Hereditary Angioedema (HAE)
Marilisa Salemi1, Francesca Di Bella2, Antonino Miragliotta2, Roberto Perricone3, Maria Domenica Guarino3, Marco Cicardi4, Andrea Zanichelli4, Valentina Selvaggio5, Francesco Arcoleo1 and Enrico Cillari1*
- Corresponding Author:
- Enrico Cillari
Department of Clinical Pathology V. Cervello Hospital
Azienda Ospedaliera Villa Sofia-Cervello, Palermo, Italy
Tel: 0039 091 6802882
Fax: 0039 091 6885343
E-mail: [email protected]
Received date: January 09, 2014; Accepted date: February 11, 2014; Published date: February 20, 2014
Citation: Salemi M, Bella FD, Miragliotta A, Perricone R, Domenica M, et al. (2014) Psychological Correlates in Subjects with Hereditary Angioedema (HAE). J Psychol Psychother 4:134. doi:10.4172/2161-0487.1000134
Copyright: © 2014 Salemi M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objectives: Hereditary Angioedema (HAE) is a rare serious medical condition caused by a deficiency of C1-inhibitor, due to mutations in its structural gene. The disease appears clinically as cutaneous swelling of the extremities, face, genitals, and trunk, painful swelling of the gastrointestinal mucosa and life threatening laryngeal edema. In this study we evaluated in HAE patients and in the relative controls the psychological status and gender differences to verify if there is a link between disease and mental status.
Methods: We studied “psychological stress”, using the Cognitive Behavioural Assessment 2.0 (CBA-2.0), in a total of 70 patients with confirmed HAE from different Italian Hospitals (41 women, 29 men; aged 17 to 78).
Results: The analysis of the majority factors of CBA-2.0 tests indicates a clear difference between male and female patients; in fact, women perceive more intensively than men the different signs of the disease (have more consciousness of the consequences that this illness provokes in their life).
Conclusion: Our data indicate that HAE is associated with emotional factors that can also complicate the clinical status of patients.