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ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Psychosis Secondary to Tuberculous Meningitis: A Case Report

Wan Syamimee Wan Ghazali* and Mohd Jazman Che Rahim
Universiti Sains Kubang Kerian, Kelantan, Malaysia
Corresponding Author : Wan Syamimee Wan Ghazali
Universiti Sains Kubang Kerian
Kelantan, Malaysia
Tel: +60 9-760 2240
E-mail: [email protected]
Received July 23, 2015; Accepted August 24, 2015; Published August 31, 2015
Citation: Ghazali WSW, Rahim MJC (2015) Psychosis Secondary to Tuberculous Meningitis: A Case Report. J Clin Case Rep 5:581. doi:10.4172/2165- 7920.1000581
Copyright: © 2015 Ghazali WSW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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Abstract

Tuberculous meningitis (TB meningitis) is a subacute meningitis known for its various form of initial manifestations, which often make early diagnosis difficult. Psychosis is a rare manifestation of this disease. We reported a case of 19-year-old woman who presented with worsening psychotic disorder of one year duration. She presented initially with social isolation with subsequent mutism and stupor. Initial brain imaging & Electroencephalography (EEG) was unremarkable. Cerebrospinal fluid (CSF) investigations revealed positive cerebrospinal fluid Mycobacterium tuberculosis polymerase chain reaction (MTB PCR). She was treated with empirical antituberculosis drugs and steroids. Subsequently her psychotic symptoms resolved. As a conclusions, the psychotic disorder was most likely caused by TB meningitis. TB meningitis should be considered in patients with no background history of psychiatric illness presenting with psychotic disorder especially in countries with high TB burden.

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