alexa Pulmonary Rehabilitation Alters Ventilatory and Cardiac Performances Profile during Exercise in Moderate to Severe Copd: 5 Cases Report
ISSN: 2161-105X

Journal of Pulmonary & Respiratory Medicine
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Case Report

Pulmonary Rehabilitation Alters Ventilatory and Cardiac Performances Profile during Exercise in Moderate to Severe Copd: 5 Cases Report

Murillo Frazão* and Wanessa Frazão

Maria Caetano Fernandes de Lima St., 225, Tambauzinho, João Pessoa-PB, Brazil

*Corresponding Author:
Murillo Frazão
Maria Caetano Fernandes de Lima St 225
Tambauzinho, João Pessoa-PB
ZIP code: 58042-050, Brazil
Tel: +5583993622322
E-mail: [email protected]

Received date: January 18, 2016; Accepted date: February 04, 2016; Published date: February 09, 2016

Citation: Frazão M, Frazão W (2016) Pulmonary Rehabilitation Alters Ventilatory and Cardiac Performances Profile during Exercise in Moderate to Severe Copd: 5 Cases Report. J Pulm Respir Med 6:320. doi:10.4172/2161-105X.1000320

Copyright: © 2016 Frazão M, et al. This is an open-access article distributed unde the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: COPD affects skeletal muscle system. Less efficient muscles generates higher ventilatory demand, which promotes a vicious cycle of dynamic hyperinflation and cardiac constraints, reducing functional capacity.

Aim: To investigate the effects of a pulmonary rehabilitation program, based on physical exercise, on ventilatory and cardiac performances profile. Methods: 5 moderate to severe COPD patients were recruited. All patients were submitted to 8 week (5 times/ week) pulmonary rehabilitation program, composed by aerobic and resistance training. The patients performed a cardiopulmonary exercise test (CPET) before and after the program.

Results: Pulmonary rehabilitation changed ventilatory (10.53 ± 5.32 vs. 28.97 ± 12.07%, p<0.05) and cardiac consumption (10.04 ± 1.80 vs. 22.88 ± 10.36%, p<0.05) at 100% work rate. Pulmonary rehabilitation also increased ventilation (20.6 ± 3.3 vs. 27.1 ± 5.9 L/min, p<0.05) and oxygen pulse (5.4 ± 1.6 vs. 7.5 ± 1.9 ml/beat, p<0.05) at 100% work rate, VO2 (610 ± 110 vs. 880 ± 230 ml/min, p<0.05) and work rate (36.8 ± 9.8 vs. 55.6 ± 14.8 W, p<0.05).

Conclusion: A 8 week pulmonary rehabilitation program improved ventilatory and cardiac performances, probably as a result of dynamic hyperinflation reduction. Peripheral muscle improvement also contributed to ventilatory and cardiac performances profile changes.


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