alexa QRS Complex Duration is a Marker of Reperfusion in Pati
ISSN: 2329-9517

Journal of Cardiovascular Diseases & Diagnosis
Open Access

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Research Article

QRS Complex Duration is a Marker of Reperfusion in Patients Presenting with Acute ST Segment Elevation Myocardial Infarction

Gehan Magdy1*, Hesham El Ashmawy1, Kamal Mahmoud2 and Asmaa Youssef2

1Department of Cardiology and Angiology, Faculty of Medicine, Alexandria University, Egypt

2Unit of Cardiology and Angiology, Medical Research Institute, Alexandria University, Egypt

*Corresponding Author:
Gehan Magdy
Department of Cardiologyand Angiology
Faculty of Medicine, Alexandria University, Egypt
Tel: 00201227108669
E-mail: [email protected]

Received date: April 08, 2017; Accepted date: May 17, 2017; Published date: May 22, 2017

Citation: Magdy G, El Ashmawy H, Mahmoud K, Youssef A (2017) QRS Complex Duration is a Marker of Reperfusion in Patients Presenting with Acute ST Segment Elevation Myocardial Infarction. J Cardiovasc Dis Diagn 5: 277. doi: 10.4172/2329-9517.1000277

Copyright: © 2017 Magdy G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Background: Acute myocardial ischemia decreases electrical conduction velocity through the ischemic myocardium, the aim of the study is to evaluate the value of the change in QRS complex duration as a marker of reperfusion in patients presenting with ST segment elevation myocardial infarction.

Methods: The study included 100 patients presented with ST segment elevation myocardial infarction, 50% treated with fibrinolysis and 50% with primary Percutaneous intervention, all patients were subjected to 12 lead electrocardiography with measurement of QRS complex duration (in millisecond) on admission, sixty and ninety minutes post reperfusion , coronary angiography was done to all patients and they were divided into two groups according to myocardial blush grade, group A (5 5%) with normal reperfusion (grade 2 and 3) and group B (45%) with impaired reperfusion (grade 0 and 1).

Results: We found that the admission QRS duration didn’t differ in the two groups (p=0.859), and QRS complex duration was found to be significantly shorter in group A at both 60 and 90 min post reperfusion (p˂0.001 for both), and found a strong positive correlation between myocardial blush grade and QRS complex narrowing at both 60 min and 90 min post reperfusion respectively (r=0.731, p˂0.001 and r=0.739, p˂0.001). A cut off 10 msec was determined to be the best QRS complex narrowing duration for prediction of reperfusion at both 60 and 90 min post reperfusion with 100% sensitivity, and a specificity of (43.64% and 58.18%) at 60 min and 90 min post reperfusion respectively.

Conclusion: QRS duration changes post reperfusion is strongly correlated to myocardial reperfusion in patients presenting with ST segment elevation myocardial infarction.

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