alexa QSAR and Synthesis of a Novel Biphenyl Carboxamide Anal
ISSN: 2329-6798

Modern Chemistry & Applications
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

QSAR and Synthesis of a Novel Biphenyl Carboxamide Analogue for Analgesic Activity

Prasanna Datar*
Sinhgad Institute of Pharmacy, Narhe, Pune, Maharashtra, India
Corresponding Author : Prasanna Datar
Sinhgad Institute of Pharmacy
Narhe, Pune, 411041
Maharashtra, India
Tel: 91-9823-161-187
E-mail: [email protected]
Received January 21, 2015; Accepted January 20, 2015; Published January 25, 2015
Citation: Datar P (2015) QSAR and Synthesis of a Novel Biphenyl Carboxamide Analogue for Analgesic Activity. Mod Chem appl 3:148. doi: 10.4172/2329-6798.1000148
Copyright: ©2015 Datar P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at
DownloadPubmed DownloadScholar Google


A compound 2-(anilino)-1-(4-phenylphenyl)ethanone was synthesized by reaction between biphenyl acid chloride and aniline. The synthesized compound was screened for analgesic activity. The selection of the compound was on the basis of QSAR study performed on the biphenyl analogs having anti-inflammatory activity. 2D QSAR study using topological descriptors revealed the important features required for the design of new potent anti-inflammatory agent. QSAR equation found in present study had r2 of 0.842 and internal predictivity of 0.69. Using QSAR results a molecule was designed to have analgesic activity.


Related Subjects

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version