alexa Quantification of Heat Map Data Displays for High-Throughput Analysis | OMICS International | Abstract
ISSN: 2153-0645

Journal of Pharmacogenomics & Pharmacoproteomics
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Research Article

Quantification of Heat Map Data Displays for High-Throughput Analysis

Paul Juneau*

Statistical Services Group, Truven Health Analytics, Boyds, USA

*Corresponding Author:
Paul Juneau
Senior Statistician, Statistical Services Group
Truven Health Analytics, Boyds, USA
Tel: 240-246-7627
E-mail: [email protected]

Received date: May 07, 2015; Accepted date: May 28, 2015; Published date: June 09, 2015

Citation: Juneau P (2015) Quantification of Heat Map Data Displays for High- Throughput Analysis 6:146. doi: 10.4172/2153-0645.1000146

Copyright: © 2015 Juneau P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Heat maps have been used as a means to visualize high-density information in settings as diverse as astronomy, business analysis, and meteorology. Discovery biology research teams have also used heat maps to visualize gene clusters in genomics investigations or to study amino acid distribution in protein sequence analysis. Commercially available software packages, like Spotfire® or SAS JMP® afford scientific investigators the ability to construct heat maps and visualize information from studies, yet do not offer any form of summary statistic that would be useful in high-throughput investigations comparing the results of a large number of data visualizations simultaneously or viewing changes in the display longitudinally (over time).

Previously, Juneau suggested the usage of Plotnick’s characterization of lacunarity (1996) for two-dimensional heat map data displays in two colors or shades. For c (c>2) discrete shades (in a monochromatic map) or hues (in a full color display), the author will suggest a modification to Plotnick’s approach using the underlying gliding box approach developed by Allain and Cloitre , but with an alteration in the means of counting features.


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