alexa Quantitative Anatomy of Taussig-Bing Anomaly
ISSN: 2161-0940

Anatomy & Physiology: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Quantitative Anatomy of Taussig-Bing Anomaly

Leo A Bockeria1, Osman A Makhachev1,2, Margarita V Gorgeeva1, Marina S Panova1, Tatiana Yu Philippkina1, Titalav Kh Khiriev1 and Sergey B Zaets1*

1Bakoulev Center for Cardiovascular Surgery, Moscow, Russia

2Dagestan Center for Cardiology and Cardiovascular surgery, Makhachkala, Russia

Corresponding Author:
Sergey B Zaets
1 Wall Street, Apt. 5B, Fort Lee, NJ 07024, USA
Tel: 1-201-873-8901
E-mail: [email protected]

Received Date: August 22, 2014; Accepted Date: September 19, 2014; Published Date: September 21, 2014

Citation: Bockeria LA, Makhachev OA, Gorgeeva MV, Panova MS, Philippkina TYu, et al. (2014) Quantitative Anatomy of Taussig-Bing Anomaly. Anat Physiol 4:158. doi: 10.4172/2161-0940.1000158

Copyright: © 2014 Bockeria LA et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Background: Taussig-Bing is one of the variants of the double outlet right ventricle. The characteristic feature of the Taussig-Bing anomaly (TBA) that makes it different from partial transposition of the great arteries is sub pulmonary ventricular septal defect. Morphometric studies of hearts with TBA are limited and in the majority of cases do not contain quantitative assessment of intracardiac structures. The aim of this study was to measure intracardiac structures (e.g. cardiac mass, diameter of valves, thickness of the myocardium), to assess their deviation from the individual norm, as well to determine how these parameters are influenced by anatomical variant of the lesion, anthropometric variability or pulmonary hypertension.
Methods: Thirty pediatric hearts with TBA underwent morphometric assessment. The median age at the moment of death was 0.4 years. All patients had pulmonary hypertension of grade I-II (n=24) or grade III-IV (n=6) per Heath- Edwards. Morphometric assessment included the measurement of the following parameters: cardiac mass, diameter of the fibrous annulus of all cardiac valves (mitral, tricuspid, aortic, and pulmonary), myocardial thickness of the both right and left ventricle. Results of valvular morphometry were compared with individual normative data presented by Schulz DM and Giordano DA, and Z-score index was calculated.
Results: Cardiac mass, right ventricular myocardial thickness and the diameter of pulmonary valve significantly exceeded normal values in TBA hearts. Cardiac mass median Z-score in TBA hearts with pulmonary hypertension of III-IV grade was significantly higher if compared to pulmonary hypertension of I-II grade. Diameters of tricuspid and pulmonary valve were significantly bigger in TBA hearts without aortic obstruction.
Conclusions: There is an increase in cardiac mass, right ventricular myocardial thickness as well as pulmonary valve diameter in TBA hearts if compared to age adjusted normal values. The degree of pulmonary hypertension may contribute to the increase in cardiac mass.

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords