alexa Questions Posed by the Use of Genetic Information for Personalized Medicine Achievements and Promises
ISSN: 2155-9627

Journal of Clinical Research & Bioethics
Open Access

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Short Communication

Questions Posed by the Use of Genetic Information for Personalized Medicine Achievements and Promises

George N Goulielmos1*, Maria I Zervou1, Agata Burska2 and Frederique Ponchel2

1Laboratory of Molecular Medicine and Human Genetics, Department of Internal Medicine, Medical School of Crete, Heraklion, Greece

2Leeds Institute of Rheumatic and Musculoskeletal Medicine, The University of Leeds, Leeds, UK

*Corresponding Author:
George N Goulielmos
Department of Medicine, Voutes
715 00 Heraklion, Crete, Greece
Tel: +302810394626
E-mail: [email protected]

Received date: December 01, 2015 Accepted date: January 19, 2016 Published date: January 21, 2016

Citation:Goulielmos GN, Zervou MI, Burska A, Ponchel F (2016) Questions Posed by the Use of Genetic Information for Personalized Medicine Achievements and Promises. J Clin Res Bioeth 7:257. doi: 10.4172/2155-9627.1000257

Copyright: © 2016 Goulielmos GN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Personalised medicine (PM) has the potential to increase therapeutic effectiveness, reduce side effects and lower cost. The identification of biomarkers predictive of the clinical response to specific treatments in subsets of patients became reality for a variety of diseases. However, a better understanding of the benefits and limitations needs to be developed at the level of the general public as well as at the level of an individual patient. The upcoming ability to characterize each patient from the genetic point of view in a comprehensive manner is believed to have the potential to transform medicine, thus enabling accurate prognosis as well as a treatment outcome prediction. However, PM holds both promise and cause for concern. Although PM promises that an individual’s genetic information may be increasingly used to prioritize medical decision making, it raises in parallel fears and questions as to whether such use could be inequitable. Thus, there are many thoughts whether the use of individual genetic information in the delivery of health care can be a cause for concern, as it may lead to genetic discrimination and other problems such as with employers and private insurance companies. Finally, the main pitfall of predictive tests for complex disease remains the putative lack of proven medical benefit. A better understanding of the benefits PM will have to be developed at the level of the general public as well as at the level of an individual patient; which will also reassure people that their genetic data is used appropriately to choose therapeutic protocols and drugs.

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