alexa Rare Genetic Cases of Heterotopic Ossification | OMICS International | Abstract
ISSN: 2161-1017

Endocrinology & Metabolic Syndrome
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Case Report

Rare Genetic Cases of Heterotopic Ossification

Ashwini Mallappa1#, Anu Vishwanath1#, Marsha C Pratt2, Klaas J Wierenga2 and Sowmya Krishnan1

#Equal Contribution

1Section of Diabetes and Endocrinology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, USA

2Section of Genetics, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, USA

corresponding Author:
Anu Vishwanath
Section of Diabetes and Endocrinology
Department of Pediatrics
University of Oklahoma Health Sciences Center, USA
E-mail: [email protected]

Received Date: August 22, 2012; Accepted Date: September 17, 2012; Published Date: September 19, 2012

Citation: Mallappa A, Vishwanath A, Pratt MC, Wierenga KJ, Krishnan S (2012) Rare Genetic Cases of Heterotopic Ossification. Endocrinol Metab Synd 1:105. doi:10.4172/2161-1017.1000105

Copyright: © 2012 Mallappa A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Heterotopic Ossification (HO) is formation of normal bone in extraskeletal tissues, namely the skin, subcutaneous tissue and deep connective tissue. Heterotopic ossification can be hereditary or nonhereditary in nature. We report two cases of rare hereditary forms of heterotopic ossification namely Fibrodysplasia Ossificans Progressiva (FOP) and Progressive Osseous Heteroplasia (POH). Hereditary forms of heterotopic ossification are progressive and severely debilitating in nature. Though these disorders are rare, awareness and knowledge about these disorders will help in early identification of such unique cases, leading to appropriate referral and management.

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