Recent Updates in the Formulation Strategies to Enhance the Bioavailability of Drugs Administered via Intranasal Route
- Corresponding Author:
- Narendar Dudhipala
Associate Professor, Vaagdevi Institute of Pharmaceutical Sciences
Warangal, Telangana-506009, India
E-mail: [email protected]
Received Date: June 30, 2016; Accepted Date: June 30, 2016 Published Date: July 07, 2016
Citation: Dudhipala N, Narala A, Bomma R (2016) Recent Updates in the Formulation Strategies to Enhance the Bioavailability of Drugs Administered via Intranasal Route. J Bioequiv Availab 8:204-207. doi:10.4172/jbb.1000295
Copyright: © 2016 Dudhipala N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Targeting drugs to the brain or Cerebrospinal fluid (CSF) is limited because of the physiological barriers like blood-brain barrier and blood-CSF barriers. Alternative non-invasive, patient compliant delivery routes like intranasal route was investigated by several research groups to target both small and large molecules. Several barriers that limit the bioavailability and research formulation strategies adopted by various research groups are discussed in brief in this review article.