alexa Relationship between Ancestry Inferred By Molecular Analysis, Self-Report and Hetero-Classification
ISSN: 2157-7145

Journal of Forensic Research
Open Access

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Research Article

Relationship between Ancestry Inferred By Molecular Analysis, Self-Report and Hetero-Classification

Pablo Abdon da Costa Francez1,2*, Adriano Ruiz Lima2, Rivelton Riverson Pereira de Almeida2 and Sidney Emanuel Batista dos Santos3

1Department of Forensic Laboratories, Laboratory for Forensic Genetics, Technical and Scientific Police in Amapá, Macapá, Amapá, Brazil

2Faculdade SEAMA, Macapá, Amapá, Brazil

3Department of Pathology, Laboratory of Human and Medical Genetics, Federal University of Pará,Belém, Pará, Brazil

*Corresponding Author:
Pablo Abdon da Costa Francez
Human and Medical Genetics Laboratory
Institute for Biological Sciences
City University Prof. José da Silveira Netto
Rua Augusto Corrêa 01, Guamá; Box: 8615
CEP: 66.075-970; Belém, Pará, Brazil
Tel: +55 91 3201-7843
E-mail: [email protected]

Received Date: July 22, 2015 ; Accepted Date: August 21, 2015 ; Published Date: August 24, 2015

Citation: Francez PADC, Lima AR, Almeida RRPD, Santos SEBD (2015) Relationship between Ancestry Inferred by Molecular Analysis, Self-Report and Hetero-Classification. J Forensic Res 6:304. doi: 10.4172/21577145.1000304

Copyright: © 2015 Francez PADC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Population stratification is the main cause of spurious results and the difficulty of replicating genetic association findings. In admixed populations, there is evidence that such proxies do not provide efficient control of stratification. We aimed to evaluate the statistical relationship between self-reported, hetero-classified and genetic ancestry, defined by categories of skin color and individual ancestry estimates and by the genotyping of 48 ancestry-informative indel markers in a sample of 130 volunteers from the city of Macapá in the Amazonian state of Amapá - Brazil. Five groups of self- reported skin color were defined: white, light brown, middle brown, dark brown and blacks, and three groups of predominant ancestry were defined: European, African and Native American. The results showed a significant correlation between skin color and predominant ancestry, self-reported and hetero-classified by volunteers, in comparison with the genetic ancestry, an important potential application of these AIMs in forensic investigations.

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