alexa Relationship between Clinical and Histopathologic Findings of 40 Periapical Lesions
ISSN: 2161-1122

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Research Article

Relationship between Clinical and Histopathologic Findings of 40 Periapical Lesions

Francisco Javier Jimenez Enriquez*, Jorge Paredes Vieyra and Fabian Paredes Ocampo

Department of Oral Surgery, Autonomous University of Baja California, 710E San Ysidro Blvd 1513, San Ysidro, California-92173, USA

*Corresponding Author:
Francisco Javier Jimenez Enriquez
Department of Oral Surgery
Autonomous University of Baja California
710E San Ysidro Blvd 1513, San Ysidro
California-92173, USA
Tel: 011526646855665
Fax: 6105913231
E-mail: [email protected]

Received date: December 17, 2014; Accepted date: January 07, 2015; Published date: January 13, 2015

Citation: Enriquez FJJ, Vieyra JP, Ocampo FP (2015) Relationship between Clinical and Histopathologic Findings of 40 Periapical Lesions. Dentistry 5:277. doi: 10.4172/2161-1122.1000277

Copyright: © 2015 Enriquez FJJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Purpose: To relate the clinical and histopathological findings of periapical inflammatory lesions treated by endodontic surgery with the results of histopathological investigation of the same lesions.

Materials and methods: Forty biopsies obtained during periapical surgery were histologically analyzed following curettage of the tissue, establishing the diagnosis as either periapical granuloma, radicular cyst, or abscess. The radiographic size of the lesion (area in cm2) before surgery and after 2 years of follow-up was measured. The evolution at 48 months after surgery was evaluated according to the criteria of von Arx and Kurt. A statistical study was made, the inter-variable relationships were studied using analysis of variance with subsequent Tukey testing and calculation of Pearson?s correlation coefficient. The hypothesis tests were conducted at the 0.05 level of significance.

Results: Results indicated that 26 (65%) were women and 14 (35%) men at a mean age of 43.54 years (range,18 to 69 years) with 40 biopsy samples. 65.5% of lesions were granulomas, 20% cysts, and 17.5% abscess. The results showed that tooth lower second molar had a high percentage of periapical lesion corresponding to periapical granuloma associated with overfilled canals.

Conclusions: The outcomes of the present study show a high number of periapical granulomas among periapical cysts and confirms that periapical granulomas are the most common periapical lesions of endodontic origin associated with persistent apical periodontitis.


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