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ISSN: 2161-0959

Journal of Nephrology & Therapeutics
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Research Article

Relationship between Patient's Demographics and Stone Composition in Men and Women

Mohamed Omar1, Manoj Monga2 and Juan C Calle3*

1Research fellow, Cleveland Clinic, Cleveland, USA

2Professor of Surgery/Urology, Stevan Streem Center of Endourology & Stone Disease, Cleveland Clinic, USA

3Departments of Urology & Nephrology, Cleveland Clinic Foundation, Cleveland, USA

*Corresponding Author:
Juan C Calle
Co-Director Kidney Stones Clinic
Glickman Urology and Kidney Institute
Department of Nephrology and Hypertension
Cleveland Clinic, 9500 Euclid Avenue
Q7-153, Cleveland, OH 44195, USA
Tel: 216 318 7105
E-mail: [email protected]

Received Date: January 28, 2015; Accepted Date: March 23, 2015; Published Date: March 30, 2015

Citation: Omar M, Calle JC, Manoj M (2015) Relationship between Patient’s Demographics and Stone Composition in Men and Women. J Nephrol Ther 5:198. doi:10.4172/2161-0959.1000198

Copyright: ©2015 Omar M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Purpose: To detect the differences in age, weight and height between three major stone groups.

Materials and Methods: We retrospectively reviewed all patients with a diagnosis of nephrolithiasis in a large healthcare network from January 2000 to July 2014, for whom information on stone composition, age, sex, weight and height was available. Patients less than 18 years were excluded. Patients were characterized by gender and the major component of their stone analysis. We used Wilcoxon rank-sum test for continuous variables to detect the significant differences and multiple logistic regression analysis to evaluate the relative risk between stone groups.

Results: 14,961 adult patients were identified. The Distribution of pure (≥ 90%) calcium oxalate, phosphate and uric acid stones in men, was (71%), (7%) and (22%) while in women it was (65%), (19%) and (16%) respectively. Males with calcium oxalate stones were taller than those with calcium phosphate by 2 cm (p=0.0006). Women with calcium phosphate stones were younger than those with calcium oxalate stones by 5 years (p=0.0001).

Conclusions: Calcium phosphate stone composition is associated with a shorter stature in men and younger age in women in relation to those with calcium oxalate stones.


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