alexa Renal Cell Carcinoma Metastasis to Thyroid Gland Associated with Papillary Thyroid Carcinoma: A Case Report and Review of the Literature | OMICS International
ISSN: 2165-7920

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Case Report

Renal Cell Carcinoma Metastasis to Thyroid Gland Associated with Papillary Thyroid Carcinoma: A Case Report and Review of the Literature

Francesco Fiorentino1, Cira Di Gioia1, Giovanni Tortorelli2, Mauro Filesi3 and Francesco Tartaglia2*
1Department of Radiological, Oncological and Pathological Sciences, “Sapienza” University of Rome, Rome, Italy
2Department of Surgical Sciences, “Sapienza” University of Rome, Rome, Italy
3Nuclear Medicine Specialist NHS, Rome, Italy
*Corresponding Author : Francesco Tartaglia
Department of Surgical Sciences
“Sapienza” University of Rome, Rome, Italy
Tel: +393403900656;
E-mail: [email protected]
Received January 09, 2016; Accepted February 20, 2016; Published February 24, 2016
Citation: Fiorentino F, Gioia CD, Tortorelli G, Filesi M, Tartaglia F (2016) Renal Cell Carcinoma Metastasis to Thyroid Gland Associated with Papillary Thyroid Carcinoma: A Case Report and Review of the Literature. J Clin Case Rep 6:715. doi:10.4172/2165-7920.1000715
Copyright: © 2016 Fiorentino F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Metastatic thyroid gland tumor is an uncommon finding in clinical practice. We report a case of metastatic renal cell carcinoma (RCC) to the thyroid gland, associated with a Papillary Thyroid Carcinoma (PTC), in a patient who had undergone left nephrectomy for RCC 6 years earlier and operated on in our Institution for a multinodular goiter disease. Immunohistochemistry can be helpful for the differential diagnosis. Metastatic cells of RCC were positive for CD10 and vimentin and negative for thyroglobulin, calcitonin, and TTF-1. Papillary carcinoma cells were positive for Cytokeratin 19, galectin-3, CD56 and Hector Battifora Mesothelial cell monoclonal antibody-1. The association between papillary thyroid carcinoma and RCC is a rare condition and maybe must not be considered a fortuitous development of 2 different neoplasms.

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