Renal Disease in Diabetes Mellitus: Recent Studies and Potential TherapiesSameena Iqbal1* and Ahsan Alam2
- *Corresponding Author:
- Sameena Iqbal
Department of Medicine, Montreal General Hospital
Division of Nephrology, 1650 Cedar Ave, L4-512
Montreal, Quebec, Canada
E-mail: [email protected]
Received date: March 13, 2013; Accepted date: May 22, 2013; Published date: May 28, 2013
Citation: Iqbal S, Alam A (2013) Renal Disease in Diabetes Mellitus: Recent Studies and Potential Therapies. J Diabetes Metab S9:006. doi:10.4172/2155-6156.S9-006
Copyright: © 2013 Iqbal S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Diabetic kidney disease is the predominant cause of end stage kidney disease in North America, estimated to be 152 per million population in 2010. New guidelines published by KDIGO on Chronic Kidney Disease classification are discussed. In light of recent clinical trials, better insight has been gained on how improve management of diabetic patients to prevent renal disease and its progression, especially with regards to metabolic and blood pressure control. Unfortunately, studies of newer therapies such as endothelin 1 antagonists and bardoxolone methyl have been disappointing, but several other possible therapeutic agents are under investigation and may provide hope for patients with diabetes mellitus in the future.