alexa Research Advances on the Treatment of Myoclonus-Dystonia Syndrome
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Review Article

Research Advances on the Treatment of Myoclonus-Dystonia Syndrome

Jie Fu*

Department of Neurology, The Hospital Affiliated of Luzhou Medical College, Sichuan, China

Corresponding Author:
Jie Fu
Department of Neurology
The Hospital Affiliated of Luzhou Medical College
Jiangyang Region, 25 Taiping Street
Luzhou, 646000, Sichuan, China
Tel: 8615181960975
E-mail: [email protected]

Received date: July 13, 2014; Accepted dat: September 06, 2014; Published date: September 15, 2014

Citation: Jie F (2014) Research Advances on the Treatment of Myoclonus-Dystonia Syndrome. J Neurol Neurophysiol 5:228. doi:10.4172/2155-9562.1000228

Copyright: © 2014 Fu J, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Myoclonus-Dystonia Syndrome is a movement disorder characterized by the association of myoclonus and
dystonia as the sole or prominent symptoms. Non-motor features may include obsessive-compulsive disorder,
depression, anxiety, personality disorders, alcohol abuse, and panic attacks. The pathogenesis of MDS is not very
clear, and the current opinions are mainly focus on gene mutations. The diagnosis is mainly based on clinical
features, and this disorder is confirmed by gene testing. Myoclonus-Dystonia Syndrome can’t be cured, and the
current therapy is mainly aimed to improve the symptoms, which includes medical and surgical treatment. All in all,
MDS remains poorly responsive to medical treatment. Although the surgical treatment develops very quickly in
recent years, due to the difficulty in predicting the range of operation and the large expense, surgical treatment is
hard to be implemented in clinical practice widely. Currently, medical treatment is still the main method, and the
surgery is considered when medication is ineffective.


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