alexa Research of Electrocardiographic and Echocardiographic
ISSN: 2167-7921

Journal of Arthritis
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Research Article

Research of Electrocardiographic and Echocardiographic Abnormalities in Rheumatoid Arthritis without Clinical Cardiovascular Events

Mouhamadou Nazirou Dodo-Siddo1*, Mouhamadou Bamba Ndiaye1, Malick Bodian1, Simon Antoine Sarr1, Souhaibou Ndongo2, Adama Kane1, Alassane Mbaye3, Tahirou Iliassou1, Habibou Harouna1, Maboury Diao1, Moustapha SARR1, Abdoul Kane3, Serigne Abdou BA1 and Thérèse Moreira Diop2
1Service of Cardiology, Hospital Aristide Le Dantec Dakar, Senegal
2Internal Medicine, Hospital Aristide Le Dantec Dakar, Senegal
3Service of Cardiology, General Hospital of Grand Yoff, Senegal
Corresponding Author : Mouhamadou Nazirou Doddo Siddo
cardiologist, Service of Cardiology
Hospital Aristide Le Dantec Dakar, Senegal
Tel: 0022796778686
E-mail: [email protected]
Received April 28, 2015; Accepted May 25, 2015; Published June 02, 2015
Citation: Dodo-Siddo MN, Ndiaye MB, Bodian M, Sarr SA, Ndongo S, e tal. (2015) Research of Electrocardiographic and Echocardiographic Abnormalities in Rheumatoid Arthritis without Clinical Cardiovascular Events. J Arthritis 4:154. doi: 10.4172/2167-7921.1000154
Copyright: © 2015 Dodo-Siddo MN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

 

Introduction: IT has been known for many years that the heart may be involved in rheumatoid arthritis. The aim of this study is to investigate the electrocardiographic and echocardiographic abnormalities in a population of Senegalese patients with rheumatoid arthritis without clinical cardiovascular disease. Patients and method: Seventy three consecutive patients between the age of 18 and 75 years admitted to the internal medicine department of University Hospital Center Aristide Le Dantec in Dakar, Senegal, with a diagnosis of rheumatoid arthritis without clinically evident cardiovascular disease. Each patient had a cardiological assessment which included a history and examination with ECG, echocardiography standard. We conducted laboratory tests (CRP, fibrinogen, ESR, Rheumatoid factors: Latex and Waaler Rose, Anti-CCP, antinuclear factors and anti-ENA antibodies). Data were analyzed using a descriptive study of the different variables with the calculation of proportions for categorical variables, and the positional parameters and dispersion for quantitative variables. Results: Sixty eight female and five patients with rheumatoid arthritis without obvious cardiac events meet the criteria of definition of the ACR 1987 were studied. The mean age was 44.17 ± 14.43 years with extremes of 18 and 75 years. The mean duration of RA was 5.93 ± 4.78 years. The concept of family inflammatory arthritis was reported in 35.60% of cases and almost one in six patients had at least a factor of cardiovascular risk (16.96%). Electrocardiographic findings were dominated by a left axis deviation in 16.44% of patients and 34 patients (46.57%) had left ventricular hypertrophy. Myocardial hyperexcitability was present in 8 patients (11.19%), including 6 premature ventricular found in patients with active RA. Twenty-six patients (35.61%) showed signs consistent with ischemia and / or myocardial injury. The echocardiography abnormalities were dominated by diastolic LV dysfunction (42.46%), increased left ventricular mass in 35.61%. Valvular leaks grades variables been highlighted regarding all orifices but rarely significant. Conclusion: Electrocardiogram and echocardiogram are a sensitive and reliable diagnostic aid for the detection of cardiac lesions in rheumatoid arthritis without clinical cardiovascular events.

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