Research of Numerical Simulation of Biomechanics on In-stent-restenosis
Aike Qiao*, Yulin Fu and Zhanzhu Zhang
College of Life Science and Bio-engineering, Beijing University of Technology, Beijing, 100124, China
- *Corresponding Author:
- Aike Qiao
College of Life Science and Bio-engineering
Beijing University of Technology
Beijing, 100124, China
E-mail: [email protected]
Received Date: February 05, 2015; Accepted Date: February 19, 2015; Published Date: February 21, 2015
Citation: Qiao A, Fu Y, Zhang Z (2015) Research of Numerical Simulation of Biomechanics on In-stent-restenosis. J Vasc Med Surg 3:181. doi: 10.4172/2329-6925.1000181
Copyright: ©2015 Qiao A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Stenting intervention is emerging as an alternative for treating the stenosis of cardiac and cerebral arteries. However, postoperative In-Stent-Restenosis (ISR) remains a challenge for medical sciences and biomechanical engineering. ISR is related not only to the stress induced by the mechanical support of stent struts on arterial wall, but also to the intimal hyperplasia induced by the hemodynamic changes. The recent research on biomechanics of stented artery was reviewed in this paper. In particular, from the perspectives of solid mechanics and hemodynamics, the research progress of stented artery using biomechanical simulation was discussed. The biomechanical factors associated with ISR were analyzed and summarized. Numerical simulation is a powerful approach for the investigation of the relationship between stenting intervention and ISR, and can provide scientific guidelines for the design of stent structure and clinical procedure of stenting intervention.