alexa Research Progress on the Biochemical Modification of Ti
ISSN: 2161-0444

Medicinal Chemistry
Open Access

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Review Article

Research Progress on the Biochemical Modification of Titanium Implant Surface

Yingjie Mao and Xiaodong Li*

The Affiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, People’s Republic of China

*Corresponding Author:
Xiaodong Li
The Affiliated Stomatology Hospital
College of Medicine, Zhejiang University
Hangzhou 310006
People’s Republic of China
Tel: 8657188206296
E-mail: [email protected]

Received date: October 04, 2014; Accepted date: November 10, 2014; Published date: November 12, 2014

Citation: Mao Y, Li X (2014) Research Progress on the Biochemical Modification of Titanium Implant Surface. Med chem 4:742-747. doi:10.4172/2161-0444.1000224

Copyright: © 2014 Mao Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Researchers are in constant search for the ideal implant surface condition in an attempt to improve osseointegration and to increase bone-to-implant contact. Although various techniques such as physicochemical and morphologic modification, have been proposed, they are still incapable of ensuring predictable results and guaranteed success. In recent years, investigators have also attempted to improve bone formation around implants via using biochemical modification. Various kinds of biomolecules have been introduced to endow the titanium surfaces bioactivities because of their certain bone-growth promoting capabilities. A review of the research progress is given in this paper concerning the biochemical modification of the implant surface.


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