Revisited Role of B Cells in AtherosclerosisPaula Blair1 and Pasquale Maffia1,2*
- *Corresponding Author:
- Pasquale Maffia
Institute of Infection, Immunity and Inflammation
College of Medical, Veterinary and Life Sciences
University of Glasgow, 120 University Place, Glasgow G128TA, UK
E-mail: [email protected]
Received date: October 08, 2012; Accepted date: October 27, 2012; Published date: October 28, 2012
Citation: Blair P, Maffia P (2012) Revisited Role of B Cells in Atherosclerosis. Pharmaceut Anal Acta 3:174. doi: 10.4172/2153-2435.1000174
Copyright: © 2012 Blair P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
B cells play a crucial role in both humoral and adaptive immune responses and are detectable in murine and human atherosclerotic arteries. Recent findings from mouse models are starting to re-define the complex role(s) of B-cells in the atherosclerosis. We will discuss the involvement of different B-cell subsets in vascular pathology and how B cells could be targeted for therapeutic utility.