alexa Reward Sensitivity and Decision Making in Depressive Episode: Are Unipolar and Bipolar Patients Different?
ISSN: 2167-1044

Journal of Depression and Anxiety
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Research Article

Reward Sensitivity and Decision Making in Depressive Episode: Are Unipolar and Bipolar Patients Different?

Rumeysa Yeni Elbay1 and Sermin Kesebir2*

1Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey

2Üsküdar University, NP Istanbul Neuropsychiatry Hospital, Istanbul, Turkey

Corresponding Author:
Sermin Kesebir
Professor of Psychiatry
Üsküdar University, NP Istanbul
Neuropsychiatry Hospital, Istanbul, Turkey
Tel: +90 216 633 0633
E-mail: [email protected]

Received March 07, 2016; Accepted April 24, 2016; Published April 28, 2016

Citation: Elbay RY, Kesebir S (2016) Reward Sensitivity and Decision Making in Depressive Episode: Are Unipolar and Bipolar Patients Different? J Depress Anxiety S2:010. doi:10.4172/2167-1044.S2-010

Copyright: © 2016 Elbay RY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objective: The aim of the present study was to determine whether unipolar and bipolar depressive episodes differ with respect to reward sensitivity and decision making.

Methods: In the present study, 25 patients diagnosed with bipolar disorder, depressive episode (BD) and 25 patients with Major depressive disorder, recurrent (UD), according to DSM-IV, were investigated. Inclusion criteria were not initiating treatment for the present period and not using antipsychotics as preventive treatment. Iowa Gambling Task was used in order to eveluate reward sensitivity and decision making process. The severity of depressive period was evaluated with Hamilton Depression Rating Scale.

Results: Overall score of IGT was found to be lower in BD group, than UD and healthy controls. HDRS scores are similar between patients with BD and UD. No relation could be shown between HDRS and IGT net scores in two depressive groups. If we consider and compare IGT scores separately for each of the five steps of the test, according to posthoc analysis results, at the first step (pre-punishment) no difference was found between BD and UD groups and healthy controls. At the second step (pre-hunch), in BD group obtained lower scores than UD group and healthy controls (BD(BD<UD=HC and BD<UD=HC).

Conclusion: Impairment in reward sensitivity and risk associated decision making processes is more pronounced in bipolar patients.


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