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ISSN: 2329-6631

Journal of Developing Drugs
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Review Article

Rheology in Pharmaceutical Formulations-A Perspective

David J Mastropietro1, Rashel Nimroozi2 and Hossein Omidian1*

1Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA

2Westside Regional Medical Center, Pharmacy Department, Plantation, Florida, USA

*Corresponding Author:
Hossein Omidian
Department of Pharmaceutical Sciences
College of Pharmacy, Nova Southeastern University
3200 South University Drive, Fort Lauderdale, FL, 33314, USA
Tel: 954-262-1334
E-mail: [email protected]

Received Date: July 29, 2013; Accepted Date: August 01, 2013; Published Date: August 06, 2013

Citation: Mastropietro DJ, Nimroozi R, Omidian H (2013) Rheology in Pharmaceutical Formulations-A Perspective. J Develop Drugs 2:108. doi: 10.4172/2329-6631.1000108

Copyright: © 2013 Mastropietro DJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Medications produced as semi-solids type product such as creams, ointments and lotions are based on emulsion or suspension type systems consisting of two or more incompatible materials. In order to be manufactured, these dosage forms need specific flow properties so they can be placed into a container, remain stable over time, dispensed, handled and properly applied to the affected area by patients. Rheology is therefore crucially important as it will directly affect the way a drug is formulated and developed, the quality of the raw and finished product, the drug efficacy, the way a patient adheres to the prescribed drug, and the overall healthcare cost. It can be concluded that there are inherent and independent factors that affect the flow property of a medicated material during every stage of its manufacturing all the way to its use.

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