Risk Factors for Late Presentation for Care among HIV-Infected Patients in Guadeloupe: 1988-2009
- *Corresponding Author:
- Elenga Narcisse, MD
Service de Pédiatrie
Centre hospitalier Andree Rosemon
Rue des Flamboyants, BP 6006-97306 Cayenne cedex
Guyane Francaise, France
E-mail: [email protected]
Received Date: July 24, 2012; Accepted Date: September 01, 2012; Published Date: September 04, 2012
Citation: Narcisse E, Marie-Therese GS, Mathieu N (2012) Risk Factors for Late Presentation for Care among HIV-Infected Patients in Guadeloupe: 1988-2009. J AIDS Clinic Res 3:166. doi:10.4172/2155-6113.1000166
Copyright: © 2012 Narcisse E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The objective of this study was to identify the factors associated with presentation for care with CD4 cell count <200/mm3. Design: A Retrospective monocentric cohort study of the Guadeloupe section of French Hospital Database for HIV was conducted. Methods: Group 1 Cohort (CD4 <200/mm3, n=1076), Group 2 (CD4 200-500, n=973) and Group 3 (CD4 >≥ 500/ mm3, n=627) patients were included between 1 January 1988 and 31 December 2009. Factors associated with late presentation (CD4 count <200 cells/μL) were assessed using descriptive statistics and ordered multivariable logistic regression. Results: At the time of diagnosis, 40.21% of patients had than less 200 CD4 lymphocytes/mm3. Age older than 30 years OR: 1.55[1.14-2.10], p=0.005, male gender OR: 1.83[1.58-2.12], p<0.0001, access to care before 1992 OR: 1.56[1.03-2.02], p=0.038 and alcohol use OR: 8.80[2.26-34.36], p=0.002 were independently associated with a low CD4 cell count. Conclusion: The findings of this study (underline the need to expand HIV testing beyond the usual facilities) may be of value in helping to achieve earlier access to treatment in HIV-infected patients in order to minimize the individual risk of morbidity and mortality.