Risk Factors for Late Preterm Births: A Case-Control StudyGian P Mandruzzato1, Giuseppe Calì2, Francesca Chiaffarino3, Giuseppe Dal Pozzo4, Luana Danti5, Vera Gerosa5, Pietro Iacobelli6, Carlo Laezza6, Francesco Macagno7, Fabio Parazzini3* and Paolo Scollo8 Mbamalu ON1*, Antunes E2, Silosini N3, Samsodien H4 and Syce J1,3
- *Corresponding Author:
- Fabio Parazzini
Department of Clinical Sciences and Community, University of Milan
Fondazione IRCCS Ca ‘Granda Ospedale Maggiore Policlinico
Via Commendation 12, 20122 Milano, Italy
Tel: +39 02 55032318
Fax: +39 02 550320252
E-mail: [email protected]
Received date: October 01, 2013; Accepted date: November 11, 2013; Published date: November 17, 2013
Citation: Mandruzzato GP, Calì G, Chiaffarino F, Pozzo GD, Danti L, et al. (2013) Risk Factors for Late Preterm Births: A Case-Control Study. Gynecol Obstet 3:182. doi: 10.4172/2161-0932.1000182
Copyright: © 2013 Mandruzzato GP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Aim: This study examines the influence of selected sociodemographic and pregnancy specific factors on the risk of Late Preterm Births (LPB) analyzing separately induced and spontaneous.
Methods: We conducted a case-control study of LPB observed in 5 Italian Centers. Cases are 305 women who delivered at 34, 35 and 36 weeks gestation. The controls were 269 women who gave birth at term (>37 weeks of gestation).
Results: Considering the total series, the risk of LPB was above unity in hypertensive women, but the OR was 6.70 (95% CI 3.25-13.82) in women with induced LPB and 0.90 (95% CI 0.35-2.32) in women with spontaneous LPB. Positive culture of vaginal smear was associated with an increased risk of LPB.
Conclusions: According to our results hypertension increases the risk of medically indicated LPB while a history of preterm birth or positive vaginal smear are associated with an increased risk of spontaneous and induces LPB.