alexa Risk Factors in the Development of Stroke in an Outpati
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Research Article

Risk Factors in the Development of Stroke in an Outpatient Cardiology Practice

Hoang M. Lai1, Wilbert S. Aronow1*, Anthony D. Mercando2, Phoenix Kalen1, Harit V. Desai1, Kaushang Gandhi1, Mala Sharma1, Harshad Amin1 and Trung M. Lai1
1From the Department of Medicine, New York Medical College, Valhalla, New York, USA
2Westchester Cardiology Associates/WestMed Medical Group and Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Corresponding Author : Wilbert S. Aronow
MD, FACC, FAHA, Cardiology Division
New York Medical College, Macy Pavilion
Room 138, Valhalla, New York, USA
Tel: (914) 493-5311
Fax: (914) 235-6274
E-mail: [email protected]
Received September 15, 2011; Accepted October 06, 2011; Published October 12, 2011
Citation: Lai HM, Aronow WS, Mercando AD, Kalen P, Desai HV, et al. (2011) A Case of 2:1 Atrio -Ventricular Block in Digoxin Toxicity. J Clinic Experiment Cardiol 2:156. doi:10.4172/2155-9880.1000156
Copyright: © 2011 Lai HM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Purpose: The aim of this study was to determine the risk factors in the development of stroke in an outpatient cardiology practice.

Methods: Chart reviews were performed in 1,599 patients (1138 men and 461 women), mean age 72 ± 12 years. Medication use and comorbidities were tabulated for each patient. Stepwise Cox regression analyses were used to analyze 45 different variables for statistical significance. The mean follow-up duration was 63 ± 55 months during 1977 to 2009.

Results: Of the 1, 599 patients, stroke occurred in 48 patients (3%) during follow-up. Stepwise Cox regression analysis showed significant independent risk factors for new stroke were statins (hazard ratio = 0.2656, 95% CI, 0.1480 to 0.4766, p <0.0001), carotid artery stenosis (hazard ratio = 3.7292, 95% CI, 1.7960 to 7.7433, p<0.001), and congestive heart failure (hazard ratio = 2.1369, 95% CI, 1.1046 to 4.1340, p <0.05).

Conclusions: In an outpatient cardiology practice, use of statins reduced the incidence of stroke by 73%. Carotid artery stenosis and congestive heart failure increased the risk of developing stroke by 3.7 times and 2.1 times, respectively.


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