Risk of Abruption Placenta in Women with Preeclampsia Undergoing Labour Induction with Misoprostol
Gueye Mamour*, Ndiaye-Gueye Mame Diarra, Cisse Mamadou lamine, Gaye Alioune and Moreau Jean Charles
Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital, 1, Pasteur Avenue, linique 3001, Dakar, Senegal
- *Corresponding Author:
- Mamour gueye
Gynaecologic and Obstetric Clinic
Aristide Le Dantec Teaching Hospital
1, Pasteur Avenue, linique 3001, Dakar, Senegal
Email: [email protected]
Received date November 19, 2014; Accepted date January 26, 2015; Published date February 02, 2015
Citation: Mamour G, Diarra NGM, lamine CM, Alioune G, Charles MJ (2015) Risk of Abruption Placenta in Women with Preeclampsia Undergoing Labour Induction with Misoprostol. J Women’s Health Care 4:224. doi:10.4172/2167-0420.1000224
Copyright: © 2015 Mamour G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Patients and Methods: This is a retrospective, descriptive and analytical study of 1.136 cases of labour induction with misoprostol performed vaginally at “Roi Baudouin” Health Centre in Dakar suburbs from 2009 to 2011. For each patient, were collected and analysed sociodemographic data, pregnancy and birth characteristics. The population was divided into 2 groups. The first group concerned patients who had preeclampsia and the second group, patients undergoing induction of labour for another indication. In each group, rate of abruption placentae was analysed. Data were entered and analysed using SPSS 17.0 software.
Results: Over 3 years, 1.136 patients underwent labour induction with misoprostol on 16.125 births (7%). The average age of patients was 27.2 years, the mean gravidity 2 and the average parity 2.47. Labour induction was performed for preeclampsia in 30.1% of cases. For 94.5% of patients, 50 μg was used as double (100 μg) was used in 63 patients (4.5%). Abruption placenta occurred in 4% of cases in patients with preeclampsia and in 0.3% of cases in patients who underwent induction for another indication (p <0.0001). 22 intrapartum deaths (2.1%) were recorded and 20 early neonatal deaths (2%). The transfer rate in neonates was 14.8%. Neonatal complications were more frequent in the preeclampsia group.
Conclusion: Induction of labour with misoprostol on preeclampsia is associated with a high risk of abruption placentae, low Apgar score at the 5th minute and intrapartum and early neonatal deaths.