Risk of Adverse Effects Using Antibiotic Prophylaxis in Ambulatory Cystoscopy: A Systematic ReviewHerney Andrés García-Perdomo1*, Eladio Jiménez-Mejías1 and Hugo López-Ramos2
- *Corresponding Author:
- Herney Andrés García-Perdomo
Department of Clinical Medicine and Public Health
University of Granada, Spain
Tel: +57 3212195102
E-mail: [email protected]
Received date: August 27, 2014; Accepted date: September 21, 2014; Published date: September 30, 2014
Citation: García-Perdomo HA, Jiménez-Mejías E, López-Ramos H (2014) Risk of Adverse Effects Using Antibiotic Prophylaxis in Ambulatory Cystoscopy: A Systematic Review. J Anesth Clin Res 5:439. doi: 10.4172/2155-6148.1000439
Copyright: 2014 García-Perdomo HA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: to determine incidence of adverse effects related to antibiotic prophylaxis compared to other interventions in patients who undergo cystoscopy with sterile urine. Methods: Search strategy (January 1980-January 2014) in Medline via PubMed, CENTRAL, and EMBASE. Additionally, we searched databases for registered trials and conference abstracts, as well as reference lists of systematic reviews and included studies. Two published randomized placebo-controlled trials (January 1, 1980 and January 31, 2014) were included in qualitative analysis with no language restrictions. Two independent reviewers collected Data. Risk of bias was evaluated with the Cochrane Collaboration recommendations. The primary outcome was incidence of adverse effects (AE).
Results: 2448 patients were found in the studies of García-Perdomo et al., and Jimenez-Cruz et al. The incidence of AE in one study was 0.7% in intervention group (nausea), no AE in control group or in the other study included. A meta-analysis was not performed.
Conclusions: There is a low incidence of adverse effects associated with antibiotic prophylaxis in cystoscopy besides we found inadequate conducting and report of this outcome in studies included.