alexa Role of Animal Models in the Study of Human Genetic Pol
ISSN: 2161-1041

Hereditary Genetics: Current Research
Open Access

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Role of Animal Models in the Study of Human Genetic Polycystic Kidney Disease

Yiqiang Cai*

Section of Nephrology, Department of Internal medicine, Yale University School of Medicine, New Haven, CT 06512

*Corresponding Author:
Yiqiang Cai
Section of Nephrology Department of Internal medicine Yale University School of Medicine New Haven CT 06512, USA
E-mail : [email protected]

Received date: January 02, 2012; Accepted date: January 09, 2012; Published date: January 13,2012

Citation: Cai Y (2012) Role of Animal Models in the Study of Human Genetic Polycystic Kidney Disease. Genetics 1:e102 doi: 10.4172/2161-1041.1000e102

Copyright: © 2012 Cai Y. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Study on animal models plays important role in understanding the molecular basis underlying the human genetic diseases. Dozens of animal models for human polycystic kidney disease (PKD) have been established and provided insightful information in better understanding of PKD in either pre-genomic or post-genomic time. Here we highlight studies of genetic animal models for PKD that brought novel insights on understanding the pathogenesis of PKD

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