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ISSN: 2329-6887

Journal of Pharmacovigilance
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Research Article

Role of the Clinical Pharmacist in Detection of Drug Therapy Problems in Critically Inpatients: Experience Report

Gabrielle Mari Rosetti Alves1, Fabiana Rossi Varallo1, Rosa Camila Lucchetta2 and Patricia de Carvalho Mastroianni1*
1Drugs and Medicines Department of the School of Pharmaceutical Sciences of Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Brazil
2Pharmacy Department of Universidade Federal do Paraná (UFPR), Brazil
Corresponding Author : Patricia de Carvalho Mastroianni
Faculdade de Ciências Farmacêuticas – UNESP
Rodovia Araraquara - Jaú
km 1 - CEP: 14801-902
Araraquara – SP, Brazil
Tel: +55 16 3301-6977
Fax: +55 16 3322-0073, +55 16 3301-6960
E-mail: [email protected]
Received July 21, 2014; Accepted July 25, 2014; Published August 1, 2014
Citation: Alves GMR, Varallo FR, Lucchetta RC, Mastroianni PC (2014) Role of the Clinical Pharmacist in Detection of Drug Therapy Problems in Critically Inpatients: Experience Report. J Pharmacovigilance 2:139. doi: 10.4172/2329-6887.1000139
Copyright: © 2014 Alves GMR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

This is an experience report on clinical pharmacy in New York, United States of America, in a teaching hospital, describing the results of drug therapy monitoring in critically ill patients, as well as interventions to solve or prevent identified drug therapy problems. The cross-sectional study was conducted by the clinical staff at the Surgical Intensive Care Unit during August 20th to 24th, 2012. Blood counts, serum levels of certain antibiotics, microbiological cultures and their antibiotic susceptibility, possible drug interactions, dosage of each drug prescribed and the compatibility between the route of administration and pharmaceutical form were assessed daily through review of electronic medical records. Twenty seven patients were followed up and 16 drug therapy problems were identified: Unnecessary drug therapy (seven), adverse drug reaction (four), needs additional drug therapy (two), noncompliance (two) and dosage too low (one). After evaluation, the drug therapy problems and their pharmaceutical interventions were reported to clinical pharmaceutical responsible for the Surgical ICU, as well as the multidisciplinary team. Further, the clinical outcomes were monitored and interventions were classified as to its acceptance. Data demonstrate that clinical pharmacists can contribute to the security and proper use of medications, as the trigger tools for intensive monitoring helps in early detection of drug therapy problems and patient safety.

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