alexa Role of Tumor Suppressor Protein p53 in Apoptosis and C
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Role of Tumor Suppressor Protein p53 in Apoptosis and Cancer Therapy

Naga Deepthi CH1*, VVL Pavan Kumar A2, Rameshbabu3 and U Indirapriyadarshini4
1Department of Microbiology, Andhra University, India
2Department of Bioinformatics, Bharath University, Chennai, India
3Department of Biochemistry, Gitam University, India
4Department of biotechnology/Indonesia cancer institute, Osmania University, Hyderabad-500017, India
Corresponding Author : Naga Deepthi CH
Department of Microbiology
Andhra University, India
E-mail: [email protected]
Received May 15, 2011; Accepted July 15, 2011; Published July 18, 2011
Citation: Naga Deepthi CH, VVL Pavan Kumar A, Rameshbabu, Indirapriyadarshini U (2011) Role of Tumor Suppressor Protein p53 in Apoptosis and Cancer Therapy. J Cancer Sci Ther S17:001. doi:10.4172/1948-5956.S17-001
Copyright: © 2011 Naga Deepthi CH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at
DownloadPubmed DownloadScholar Google
 

Abstract

TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers demonstrate the inactivation of the p53 pathway. Mutant p53 not only, no longer, functions as a tumor suppressor but can also exert tumor-promoting effects. The basic function of p53 is to respond to cellular stress. We here in this review article discusses about the recent advances in p53 research, mainly focusing on apoptosis and therapy for human cancer. Hence, this review aims to update the current related articles and provide a further understanding about such molecular changes relevant to trigger imbalances in the regulation of apoptosis in cancer.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords