alexa Rosai-Dorfman Disease in a 23-Year-Old Patient
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Rosai-Dorfman Disease in a 23-Year-Old Patient

Hela Hariz1*, Sameh Marzouk1, Raida Ben Salah1, Noura Saidi1, Moez Jallouli1, Tahia Boudawara2 and Zouhir Bahloul1
1Department of Internal Medicine, Hédi Chaker University Hospital, Sfax, Tunisia
2Department of Anatomopathology, Habib Bourguiba University Hospital, Sfax, Tunisia
Corresponding Author : Hela Hariz
Department of Internal Medicine
Hedi Chaker University Hospital
El Ain Road, 3000 Sfax, Tunisia
E-mail: [email protected]
Received February 04, 2013; Accepted July 04, 2013; Published July 08, 2013
Citation: Hariz H, Marzouk S, Salah RB, Saidi N, Jallouli M, et al. (2013) Rosai-Dorfman Disease in a 23-Year-Old Patient. J Clin Case Rep 3:291. doi:10.4172/2165-7920.1000291
Copyright: © 2013 Hariz H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Rosai-Dorfman Disease (RDD) also known as Sinus Histiocytosis With Massive Lymphadenopathy (SHML) is a rare and benign non- Langerhans histiocytosis. First described in 1965 by Destombes [1] then in 1969 by Rosai and Dorfman, this disease is characterized by benign histiocytic proliferation with frequent lymphophagocytosis (emperipolesis) [2]. All ages are affected but most of the patients present before age 20, with a slight male predominance [3]. Rosai-Dorfman disease usually presents as bilateral, massive and painless cervical lymphadenopathy [2]. Extra-nodal involvement is found in 30-40% of cases and is more common in the head and neck region [3]. The disease is often benign and self limiting requiring only observation. In some cases, the condition can be severe. Several treatments have been used with varying efficiency [4]. We report a case of RDD in a male Tunisian patient treated and followed up in our department.

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