Ruptured Mycotic Aortic Aneurysm Secondary to Escherichia Coli Bacteremia in an HIV-Positive Patient
Nicholas David Ward and Jean Marie Ruddy*
Department of Surgery, Medical University of South Carolina, USA
- *Corresponding Author:
- Jean Marie Ruddy
Department of Surgery
Medical University of South Carolina, USA
E-mail: [email protected]
Received Date: March 03, 2017; Accepted Date: March 22, 2017; Published Date: March 27, 2017
Citation:Ward ND, Ruddy JM (2017) Ruptured Mycotic Aortic Aneurysm Secondary to Escherichia coli Bacteremia in an HIV-Positive Patient. J Clin Case Rep 7:941. doi: 10.4172/2165-7920.1000941
Copyright: © 2017 Ward ND, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Mycotic aortic aneurysms are an aggressive form of degenerative remodeling reported more commonly in immunosuppressed patients. These aneurysms carry a high risk of progression to rupture, fulminant sepsis, and death, and therefore require prompt operative intervention. The human immunodeficiency virus (HIV) has also been associated with a broad spectrum of vascular disease, including development of aneurysms, however these have typically been identified in the peripheral vasculature. We report the case of a 71-year-old, HIV-positive male who presented with Escherichia coli bacteremia and aortitis which rapidly progressed to a ruptured infrarenal mycotic aortic aneurysm. He was managed successfully with open debridement and in situ implantation of a rifampin-soaked prosthetic graft as well as long-term antibiotic therapy. Here, we review the epidemiology, pathophysiology, and optimal surgical treatment of mycotic aortic aneurysms.