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ISSN: 2155-983X

Journal of Nanomedicine & Biotherapeutic Discovery
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Research Article

Salivary Antioxidant Power of Passive Smokers

Azadbakht M1, Sariri R1*, Soltani FM1, Ghafoori H1, Aghamaali MR1 and Erfani Karimzadeh Toosi A2

1Department of Biochemistry, University of Guilan, Rasht, Iran

2Guilan University of Medical Sciences, Rasht, Iran

*Corresponding Author:
Sariri R
Department of Biochemistry, Faculty of Sciences
University of Guilan, Iran
Tel: +981333758668
E-mail: [email protected]

Received date: May 26, 2016; Accepted date: June 17, 2016; Published date: June 23, 2016

Citation: Azadbakht M, Sariri R, Soltani FM, Ghafoori H, Aghamaali MR, et al. (2016) Salivary Antioxidant Power of Passive Smokers. J Nanomedine Biotherapeutic Discov 6:142. doi:10.4172/2155-983X.1000142

Copyright: © 2016 Azadbakht M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Introduction: Cigarette smoke has been proven to be injurious to both oral cavity and internal body environment. Passive smokers could also suffer from smoke. Saliva, the first biological fluid which encounters cigarette smoke, contains antioxidant defense system to reduce the toxic effects of cigarette smoke. Objectives: The aim was investigating salivary

antioxidants

of passive smokers as compared to non-smokers. Method: Un-stimulated whole saliva samples, obtained from passive smokers and non-smokers, were centrifuged and stored at -70°C. The antioxidant power was then measure using various methods. Results: No statistically significant difference in antioxidant capacity, total phenol, and radical scavenging activity of saliva between studied groups was found. However, concentration of uric acid, the important antioxidant of saliva, was decreased dramatically in passive smokers. Conclusions: It was suggested that measurement of antioxidants in salivary fluid could be a useful noninvasive method to investigate abnormalities related to oral cavity and

gastrointestinal tract.

 

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