alexa Scanning and Transmission Electron Microscope Examination of Cochlea Hair and Pillar Cells from the Ear of the Mongolian Gerbil (Meriones unguiculatus) | Abstract
ISSN: 2161-0940

Anatomy & Physiology: Current Research
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Research Article

Scanning and Transmission Electron Microscope Examination of Cochlea Hair and Pillar Cells from the Ear of the Mongolian Gerbil (Meriones unguiculatus)

JM Lovell1,3*, M Brosch1, E Budinger1, J Goldschmidt1, H Scheich1, S Tschorn1, U Wendt2 and W Zuschratter1

1Leibniz Institute for Neurobiology, Magdeburg, Germany

2Institute of Materials and Joining Technology, Otto von Guericke University, Magdeburg, Germany

3Deutsches Zentrum fur Neurodegenerative Erkrankungen (DZNE), Bonn, Germany

*Corresponding Author:
JM Lovell
Leibniz Institute for Neurobiology
Magdeburg, Deutsches Zentrum fur Neurodegenerative Erkrankungen (DZNE)
Bonn, Germany
Tel: +49-391-6263-32
E-mail: [email protected]

Received date March 21, 2012; Accepted date June 23, 2012; Published date June 25, 2012

Citation: Lovell JM, Brosch M, Budinger E, Goldschmidt J, Scheich H, et al. (2012) Scanning and Transmission Electron Microscope Examination of Cochlea Hair and Pillar Cells from the Ear of the Mongolian Gerbil (Meriones unguiculatus). Anat Physiol 2:106. doi: 10.4172/2161-0940.1000106

Copyright: © 2012 Lovell JM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The rodent inner ear and especially from the Mongolian Gerbil (Meriones unguiculatus) has received considerable attention in recent years for hearing research purposes, with models employed, for example, comprehension of age and noise related hearing loss, genetic disorders in auditory processing and the effects of ototoxic drugs. To aid both histological and physiological investigations, topographic details of the hair cells along the organ of Corti are imaged using the Scanning Electron Microscope (SEM) to reveal the overall length of the cochlea and to indicate the number of hair cells present. This information is of use in, for example, surgical planning for the implantation of electrodes and other interfaces and for pharmacological research purposes where the effects of certain drugs and other agents on the ear can be determined pathologically.

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