alexa Search for an Herbal Medicine: Anti-inflammatory Activity of Methanolic Extract of Haldina cordifolia
e-ISSN: 2321-6182 p-ISSN: 2347-2332

Research & Reviews: Journal of Pharmacognosy and Phytochemistry
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Research Article

Search for an Herbal Medicine: Anti-inflammatory Activity of Methanolic Extract of Haldina cordifolia

Pragyandip P Dash1, Anuradha Mishra2, Devdutt Chaturvedi1,3*, Swan SR4

1Laboratory of Medicinal Chemistry, Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow Campus, Lucknow-226028, UP, India.

2Faculty of Pharmacy, Integral University, Lucknow-226026, UP, India.

3Department of Applied Chemistry, Amity School of Applied Sciences, Amity University Uttar Pradesh,Lucknow Campus, Lucknow-226028, UP, India

4Faculty of Pharmacy, Sherwood College of Pharmacy, Barabanki-225001, UP, India

Corresponding Author:
Devdutt Chaturvedi
Laboratory of Medicinal Chemistry, Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow Campus, Lucknow, India.
E-mail: [email protected]

Received: 26/10/2015 Accepted: 21/12/2015 Published: 30/12/2015

 

Abstract

 Haldina cordifolia had been extensively used for its reported biological action in indigenous organization of medicine. The at hand investigation was carried out to discover the anti-inflammatory effect of methanolic extract of Haldina cordifolia in albino rats. The anti-inflammatory activity was evaluated by means of acute inflammatory model like carrageenan induced paw edema and chronic inflammatory model like cotton pellet induced granuloma respectively. The methanolic extract in different doses (100,200, and 400 mg/kg, p.o) exhibited dose dependent and significant anti-inflammatory activity in acute (carageenan induced hind paw edema, p<0.05) and chronic (cotton pellet granuloma formation, p<0.05) model of inflammation.

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