Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis
- *Corresponding Author:
- Denise Miyamoto
University of São Paulo Medical School
São Paulo-State of São Paulo, Brazil
E-mail: [email protected]
Received date: April 25, 2016 ; Accepted date: May 20, 2016 ; Published date: May 25, 2016
Citation: Miyamoto D, Wang B, Miyamoto C, Aoki V, Lim LA, et al. (2016) Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis. J Clin Exp Dermatol Res 7:353. doi:10.4172/2155-9554.1000353
Copyright: © 2016 Miyamoto D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sebaceous cell carcinoma continues to defy clinicians and pathologists in terms of early diagnosis. The tumor may be mistaken as benign lesions such as chalazion and blepharitis, and also as malignant neoplasms, mainly basal cell carcinoma and squamous cell carcinoma. Despite advances in immunohistochemical analysis and treatment options during the last decades, morbidity and metastasis rates remain high. Prognosis is strongly related to the length of time between diagnosis and initiation of treatment, which reinforces the importance of early recognition of this condition. This article reviews key features of sebaceous cell carcinoma, from epidemiology to treatment, and new strategies to improve outcome.