alexa Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

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Review Article

Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis

Denise Miyamoto1*, Beatrice Wang2, Cristina Miyamoto3,4, Valeria Aoki1, Li Anne Lim4, Paula Blanco4 and Miguel N Burnier4

1Department of Dermatology, University of São Paulo Medical School, Brazil

2Department of Dermatology, McGill University, Canadan

3Department of Ophthalmology, Federal University of São Paulo, Brazil

4From the Henry C. Witelson Ocular Pathology Laboratory, McGill University, Canada

*Corresponding Author:
Denise Miyamoto
University of São Paulo Medical School
São Paulo-State of São Paulo, Brazil
Tel: 514-934-76129
E-mail: [email protected]

Received date: April 25, 2016 ; Accepted date: May 20, 2016 ; Published date: May 25, 2016

Citation: Miyamoto D, Wang B, Miyamoto C, Aoki V, Lim LA, et al. (2016) Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis. J Clin Exp Dermatol Res 7:353. doi:10.4172/2155-9554.1000353

Copyright: © 2016 Miyamoto D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Sebaceous cell carcinoma continues to defy clinicians and pathologists in terms of early diagnosis. The tumor may be mistaken as benign lesions such as chalazion and blepharitis, and also as malignant neoplasms, mainly basal cell carcinoma and squamous cell carcinoma. Despite advances in immunohistochemical analysis and treatment options during the last decades, morbidity and metastasis rates remain high. Prognosis is strongly related to the length of time between diagnosis and initiation of treatment, which reinforces the importance of early recognition of this condition. This article reviews key features of sebaceous cell carcinoma, from epidemiology to treatment, and new strategies to improve outcome.

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